Focus on Methodology: Salivary bioscience and research on adolescence: An integrated perspective

Douglas A. Granger, Christine K. Fortunato, Emilie K. Beltzer, Marta Virag, Melissa A. Bright, Dorothée Out

Research output: Contribution to journalArticlepeer-review

134 Scopus citations


The characterization of the salivary proteome and advances in biotechnology create an opportunity for developmental scientists to measure multi-level components of biological systems in oral fluids and identify relationships with developmental processes and behavioral and social forces. The implications for developmental science are profound because from a single oral fluid specimen, information can be obtained about a broad array of biological systems and the genetic polymorphisms related to their function. The purpose of this review is to provide a conceptual and tactical roadmap for investigators interested in integrating these measurement tools into research on adolescent health and development.

Original languageEnglish (US)
Pages (from-to)1081-1095
Number of pages15
JournalJournal of Adolescence
Issue number4
StatePublished - Aug 2012
Externally publishedYes


  • Adolescence
  • Alpha-amylase
  • Analytical strategy
  • Antibodies
  • Biobehavioral
  • Cortisol
  • DHEA
  • DNA
  • Development
  • Inflammation
  • Methods
  • Saliva analytes
  • Saliva collection
  • Testosterone

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Social Psychology
  • Developmental and Educational Psychology
  • Psychiatry and Mental health


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