@article{dd3598c34e254830a3a1ace83b9c1d3d,
title = "Femtosecond X-ray diffraction from an aerosolized beam of protein nanocrystals:",
abstract = "High-resolution Bragg diffraction from aerosolized single granulovirus nanocrystals using an X-ray free-electron laser is demonstrated. The outer dimensions of the in-vacuum aerosol injector components are identical to conventional liquid-microjet nozzles used in serial diffraction experiments, which allows the injector to be utilized with standard mountings. As compared with liquid-jet injection, the X-ray scattering background is reduced by several orders of magnitude by the use of helium carrier gas rather than liquid. Such reduction is required for diffraction measurements of small macromolecular nanocrystals and single particles. High particle speeds are achieved, making the approach suitable for use at upcoming high-repetition-rate facilities.",
keywords = "X-ray diffraction, aerosols, nanocrystals",
author = "Salah Awel and Richard Kirian and Wiedorn, {Max O.} and Beyerlein, {Kenneth R.} and Nils Roth and Horke, {Daniel A.} and Dominik Oberth{\"u}r and Juraj Knoska and Valerio Mariani and Andrew Morgan and Luigi Adriano and Alexandra Tolstikova and Xavier, {P. Lourdu} and Oleksandr Yefanov and Andrew Aquila and Anton Barty and Shatabdi Roy-Chowdhury and Hunter, {Mark S.} and Daniel James and Robinson, {Joseph S.} and Uwe Weierstall and Rode, {Andrei V.} and Sa{\v s}a Bajt and Jochen K{\"u}pper and Chapman, {Henry N.}",
note = "Funding Information: Use of the Linac Coherent Light Source (LCLS), SLAC National Accelerator Laboratory, is supported by the US Department of Energy, Office of Science, Office of Basic Energy Sciences under contract No. DE-AC02-76SF00515. Parts of the sample delivery system used at LCLS for this research were funded by the NIH grant P41GM103393, formerly P41RR001209. In addition to DESY, this work has been supported by the excellence cluster {\textquoteleft}The Hamburg Center for Ultrafast Imaging – Structure, Dynamics and Control of Matter at the Atomic Scale{\textquoteright} of the Deutsche Forschungsgemeinschaft (CUI, DFG-EXC1074), the Gottfried Wilhelm Leibniz Program of the DFG, the European Research Council under the European Union{\textquoteright}s Seventh Framework Programme (FP7/2007–2013) through the Synergy Grant AXSIS (ERC-2013-SyG 609920) and the Consolidator Grant COMOTION (ERC-K{\"u}pper-614507), the Helmholtz Association {\textquoteleft}Initiative and Networking Fund{\textquoteright}, and the Australian Research Council{\textquoteright}s Discovery Projects funding scheme (DP170100131). RAK acknowledges support from an NSF STC award (1231306). Publisher Copyright: {\textcopyright} Salah Awel et al. 2018.",
year = "2018",
month = feb,
doi = "10.1107/S1600576717018131",
language = "English (US)",
volume = "51",
pages = "133--139",
journal = "Journal of Applied Crystallography",
issn = "0021-8898",
publisher = "International Union of Crystallography",
number = "1",
}