Abstract
A practical example is given of how a newly developed stereological estimator of particle number, the disector, can be used to make estimates of neuron number in the dentate gyrus of rats. The estimates are free of biases related to lost caps, overprojection and assumptions about size, shape and orientation of the objects that are counted. The disector principle and the practical considerations relating to histological preparations and sampling are presented.
Original language | English (US) |
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Pages (from-to) | 167-172 |
Number of pages | 6 |
Journal | Brain Research |
Volume | 448 |
Issue number | 1 |
DOIs | |
State | Published - May 10 1988 |
Externally published | Yes |
Keywords
- Dentate gyrus
- Disector
- Granule cell
- Morphometrics
- Stereology
ASJC Scopus subject areas
- General Neuroscience
- Molecular Biology
- Clinical Neurology
- Developmental Biology