Abstract
This chapter highlights the various environmental stimuli which can be utilized as a trigger for in situ formation of injectable hydrogel systems, specifically to provide a more efficient and localized method for controlled delivery of drugs and molecules. These components include temperature, electric field, pH, light, magnetic field, pressure and ionic strength, as well as biomolecular stimuli such as antigens, enzymes, thrombin, and glucose. The properties of each stimulus are described as well as their particular uses in biomedical applications.
Original language | English (US) |
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Title of host publication | Injectable Biomaterials |
Subtitle of host publication | Science and Applications |
Publisher | Elsevier Inc. |
Pages | 263-297 |
Number of pages | 35 |
ISBN (Print) | 9781845695880 |
DOIs | |
State | Published - Jan 2011 |
Keywords
- Antigen
- Electric field
- Enzyme
- Glucose
- Hydrogel
- Ionic strength
- Light
- Magnetic field
- PH
- Poly(N-isopropyl acrylamide)
- Pressure
- Temperature
- Thrombin
ASJC Scopus subject areas
- General Materials Science