Effectiveness of atomic and polyatomic primary ions for organic secondary ion mass spectrometry

Chris W. Diehnelt, Michael J. Van Stipdonk, Emile A. Schweikertl

Research output: Contribution to journalArticlepeer-review

25 Scopus citations


With the increased application of polyatomic primary ions for organic secondary ion mass spectrometry, a method to compare the performance of the various available projectiles is needed. In this work, primary ion performance was evaluated based on analyte-specific secondary ion yield, the amount of fragmentation, and the amount of metastable decay induced by each primary ion. These measurements were used to construct a projectile efficiency number for each primary ion applied to a specific analyte. An organic acid, phospholipids, and alkyl sulfates, prepared as multilayer and monolayer surfaces were analyzed with various atomic and polyatomic primary ions. It was found that polyatomic primary ions are best suited for multilayer organic samples whereas atomic primary ions are most effective for monolayer organic samples. Results are compared to other studies that measure the ion formation efficiency of various primary ions.

Original languageEnglish (US)
Pages (from-to)111-122
Number of pages12
JournalInternational Journal of Mass Spectrometry
Issue number1-2
StatePublished - Apr 12 2001
Externally publishedYes


  • Desorption
  • Metastability
  • Polyatomic primary ions
  • Secondary ion mass spectrometry

ASJC Scopus subject areas

  • Instrumentation
  • Condensed Matter Physics
  • Spectroscopy
  • Physical and Theoretical Chemistry


Dive into the research topics of 'Effectiveness of atomic and polyatomic primary ions for organic secondary ion mass spectrometry'. Together they form a unique fingerprint.

Cite this