Effect of induced alkalosis on the power-duration relationship of "all-out" exercise

Anni Vanhatalo, Lars R. McNaughton, Jason Siegler, Andrew M. Jones

Research output: Contribution to journalArticlepeer-review

51 Scopus citations


Purpose: We tested the hypotheses that sodium bicarbonate (NaHCO3) ingestion would result in no alteration in critical power (CP) but would improve performance in a 3-min all-out cycling test by increasing the total amount of work done above CP (W′). Methods: Eight habitually active subjects completed 3-min all-out sprints against fixed resistance in a blind randomized design after a dose of 0.3 g•kg body mass of NaHCO3 and 0.045 g•kg body mass of sodium chloride (placebo; PL trial). Blood acid-base status was assessed from arterialized fingertip blood samples before and after exercise. The CP was calculated as the mean power output during the final 30 s of the test, and the W′ was estimated as the power-time integral >CP. Results: The NaHCO3 dose was effective in inducing preexercise alkalosis as indicated by changes in blood pH (PL = 7.40 ± 0.02 vs NaHCO3 = 7.46 ± 0.01, P < 0.001), [bicarbonate] (PL = 21.9 ± 3.0 vs NaHCO3 = 29.0 ± 3.8 mM, P < 0.05), and base excess (PL =-1.9 ± 2.5 vs NaHCO3 = 5.0 ± 3.0 mM, P < 0.05). There were no significant differences in the total work done (PL = 62.8 ± 10.1 vs NaHCO3 = 62.7 ± 10.1 kJ), the CP (PL = 248 ± 50 vs NaHCO3 = 251 ± 51 W), or the W′ (PL = 18.2 ± 6.4 vs NaHCO3 = 17.5 ± 6.0 kJ) estimates between treatments. Conclusions: Despite notably enhanced blood-buffering capacity, NaHCO3 ingestion had no effect on the W′, the CP, or the overall performance during 3 min of all-out cycling. It is concluded that preexercise blood alkalosis had no influence on the power-duration relationship for all-out exercise.

Original languageEnglish (US)
Pages (from-to)563-570
Number of pages8
JournalMedicine and science in sports and exercise
Issue number3
StatePublished - Mar 2010
Externally publishedYes


  • Anaerobic work capacity
  • Critical power
  • Sodium bicarbonate
  • Sprint cycling

ASJC Scopus subject areas

  • Orthopedics and Sports Medicine
  • Physical Therapy, Sports Therapy and Rehabilitation


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