Abstract
This chapter discusses the design and applications of injectable biomaterials for the controlled delivery of drugs, proteins, and other therapeutics for the treatment of various diseases. The first half of the chapter describes in situ forming drug delivery systems which are injectable as a liquid, forming a solid or semi-solid depot after injection which then releases the drug. The second half of the chapter discusses particulate drug delivery systems which are often injected into the circulation. Emphasis is placed on clinical applications as well as stimuli responsive and/or targeted drug delivery. Design choices relevant to each class of injectable system are highlighted.
Original language | English (US) |
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Title of host publication | Injectable Biomaterials |
Subtitle of host publication | Science and Applications |
Publisher | Elsevier Inc. |
Pages | 95-141 |
Number of pages | 47 |
ISBN (Print) | 9781845695880 |
DOIs | |
State | Published - Jan 2011 |
Keywords
- Drug delivery
- Injectable drug depot
- Nanoparticles
- Targeted cancer chemotherapy
ASJC Scopus subject areas
- General Materials Science