Detection of dihydrofolate reductase conformational change by fret using two fluorescent amino acids

Medicine & Life Sciences

• Tetrahydrofolate Dehydrogenase 88%
• dihydrofolate reductase type II 70%
• Amino Acids 46%
• Energy Transfer 32%
• (7-hydroxycoumarin-4-yl) ethylglycine 21%
• Trimethoprim 10%
• Proteins 6%
• 4-biphenyl-l-phenylalanine 1%

Engineering & Materials Science

• Oxidoreductases 100%
• Amino acids 78%
• Fluorophores 27%
• Proteins 10%
• Forster resonance energy transfer 8%
• Conformations 6%
• Irradiation 5%
• Monitoring 3%

Chemical Compounds

• Dihydrofolates 83%
• Acid 22%
• Energy Transfer 9%
• Trimethoprim 7%
• Fluorescence Resonance Energy Transfer 5%
• Protein 4%
• Probe 3%
• Surface 1%