Dating the origins of the maize-adapted strain of maize streak virus, MSV-A

Gordon W. Harkins; Darren P. Martin; Siobian Duffy; Aderito L. Monjane; Dionne N. Shepherd; Oliver P. Windram; Betty E. Owor; Lara Donaldson; Tania van Antwerpen; Rizwan A. Sayed; Bradley Flett; Moses Ramusi; Edward P. Rybicki; Michel Peterschmitt; Arvind Varsani

doi:10.1099/vir.0.015537-0

Dating the origins of the maize-adapted strain of maize streak virus, MSV-A

Gordon W. Harkins, Darren P. Martin, Siobian Duffy, Aderito L. Monjane, Dionne N. Shepherd, Oliver P. Windram, Betty E. Owor, Lara Donaldson, Tania van Antwerpen, Rizwan A. Sayed, Bradley Flett, Moses Ramusi, Edward P. Rybicki, Michel Peterschmitt, Arvind Varsani

Research output: Contribution to journal › Article › peer-review

46 Scopus citations

Abstract

Maize streak virus (MSV), which causes maize streak disease (MSD), is one of the most serious biotic threats to African food security. Here, we use whole MSV genomes sampled over 30 years to estimate the dates of key evolutionary events in the 500 year association of MSV and maize. The substitution rates implied by our analyses agree closely with those estimated previously in controlled MSV evolution experiments, and we use them to infer the date when the maize-adapted strain, MSV-A, was generated by recombination between two grass-adapted MSV strains. Our results indicate that this recombination event occurred in the mid-1800s, ∼20 years before the first credible reports of MSD in South Africa and centuries after the introduction of maize to the continent in the early 1500s. This suggests a causal link between MSV recombination and the emergence of MSV-A as a serious pathogen of maize.

Original language	English (US)
Pages (from-to)	3066-3074
Number of pages	9
Journal	Journal of General Virology
Volume	90
Issue number	12
DOIs	https://doi.org/10.1099/vir.0.015537-0
State	Published - 2009
Externally published	Yes

ASJC Scopus subject areas

Virology

Access to Document

10.1099/vir.0.015537-0

Cite this

Harkins, G. W., Martin, D. P., Duffy, S., Monjane, A. L., Shepherd, D. N., Windram, O. P., Owor, B. E., Donaldson, L., van Antwerpen, T., Sayed, R. A., Flett, B., Ramusi, M., Rybicki, E. P., Peterschmitt, M., & Varsani, A. (2009). Dating the origins of the maize-adapted strain of maize streak virus, MSV-A. Journal of General Virology, 90(12), 3066-3074. https://doi.org/10.1099/vir.0.015537-0

Harkins, GW, Martin, DP, Duffy, S, Monjane, AL, Shepherd, DN, Windram, OP, Owor, BE, Donaldson, L, van Antwerpen, T, Sayed, RA, Flett, B, Ramusi, M, Rybicki, EP, Peterschmitt, M & Varsani, A 2009, 'Dating the origins of the maize-adapted strain of maize streak virus, MSV-A', Journal of General Virology, vol. 90, no. 12, pp. 3066-3074. https://doi.org/10.1099/vir.0.015537-0

@article{cfa55dd8996a48dd80af7626a0b587ac,

title = "Dating the origins of the maize-adapted strain of maize streak virus, MSV-A",

abstract = "Maize streak virus (MSV), which causes maize streak disease (MSD), is one of the most serious biotic threats to African food security. Here, we use whole MSV genomes sampled over 30 years to estimate the dates of key evolutionary events in the 500 year association of MSV and maize. The substitution rates implied by our analyses agree closely with those estimated previously in controlled MSV evolution experiments, and we use them to infer the date when the maize-adapted strain, MSV-A, was generated by recombination between two grass-adapted MSV strains. Our results indicate that this recombination event occurred in the mid-1800s, ∼20 years before the first credible reports of MSD in South Africa and centuries after the introduction of maize to the continent in the early 1500s. This suggests a causal link between MSV recombination and the emergence of MSV-A as a serious pathogen of maize.",

author = "Harkins, {Gordon W.} and Martin, {Darren P.} and Siobian Duffy and Monjane, {Aderito L.} and Shepherd, {Dionne N.} and Windram, {Oliver P.} and Owor, {Betty E.} and Lara Donaldson and {van Antwerpen}, Tania and Sayed, {Rizwan A.} and Bradley Flett and Moses Ramusi and Rybicki, {Edward P.} and Michel Peterschmitt and Arvind Varsani",

year = "2009",

doi = "10.1099/vir.0.015537-0",

language = "English (US)",

volume = "90",

pages = "3066--3074",

journal = "Journal of General Virology",

issn = "0022-1317",

publisher = "Society for General Microbiology",

number = "12",

}

TY - JOUR

T1 - Dating the origins of the maize-adapted strain of maize streak virus, MSV-A

AU - Harkins, Gordon W.

AU - Martin, Darren P.

AU - Duffy, Siobian

AU - Monjane, Aderito L.

AU - Shepherd, Dionne N.

AU - Windram, Oliver P.

AU - Owor, Betty E.

AU - Donaldson, Lara

AU - van Antwerpen, Tania

AU - Sayed, Rizwan A.

AU - Flett, Bradley

AU - Ramusi, Moses

AU - Rybicki, Edward P.

AU - Peterschmitt, Michel

AU - Varsani, Arvind

PY - 2009

Y1 - 2009

N2 - Maize streak virus (MSV), which causes maize streak disease (MSD), is one of the most serious biotic threats to African food security. Here, we use whole MSV genomes sampled over 30 years to estimate the dates of key evolutionary events in the 500 year association of MSV and maize. The substitution rates implied by our analyses agree closely with those estimated previously in controlled MSV evolution experiments, and we use them to infer the date when the maize-adapted strain, MSV-A, was generated by recombination between two grass-adapted MSV strains. Our results indicate that this recombination event occurred in the mid-1800s, ∼20 years before the first credible reports of MSD in South Africa and centuries after the introduction of maize to the continent in the early 1500s. This suggests a causal link between MSV recombination and the emergence of MSV-A as a serious pathogen of maize.

AB - Maize streak virus (MSV), which causes maize streak disease (MSD), is one of the most serious biotic threats to African food security. Here, we use whole MSV genomes sampled over 30 years to estimate the dates of key evolutionary events in the 500 year association of MSV and maize. The substitution rates implied by our analyses agree closely with those estimated previously in controlled MSV evolution experiments, and we use them to infer the date when the maize-adapted strain, MSV-A, was generated by recombination between two grass-adapted MSV strains. Our results indicate that this recombination event occurred in the mid-1800s, ∼20 years before the first credible reports of MSD in South Africa and centuries after the introduction of maize to the continent in the early 1500s. This suggests a causal link between MSV recombination and the emergence of MSV-A as a serious pathogen of maize.

UR - http://www.scopus.com/inward/record.url?scp=70849104037&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=70849104037&partnerID=8YFLogxK

U2 - 10.1099/vir.0.015537-0

DO - 10.1099/vir.0.015537-0

M3 - Article

C2 - 19692547

AN - SCOPUS:70849104037

SN - 0022-1317

VL - 90

SP - 3066

EP - 3074

JO - Journal of General Virology

JF - Journal of General Virology

IS - 12

ER -

Dating the origins of the maize-adapted strain of maize streak virus, MSV-A

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this