TY - GEN
T1 - Classification of Neurological Gait Disorders Using Multi-task Feature Learning
AU - Papavasileiou, Ioannis
AU - Zhang, Wenlong
AU - Wang, Xin
AU - Bi, Jinbo
AU - Zhang, Li
AU - Han, Song
N1 - Funding Information:
The authors want to acknowledge Dr. Nancy Byl and Ms. Sophia Coo at UCSF for organizing the human subject study, and the patients who participated in the study for their cooperation. The authors would like to also thank Dr. Masayoshi Tomizuka at UC Berkeley for his early support developing the smart shoes. This work was partially supported by National Science Foundation (NSF) grants DBI-1356655 and IIS-1320586. Jinbo Bi was also supported by NSF grants CCF-1514357, IIS-1407205, and IIS-1447711 and the grants from National Institutes of Health R01DA037349 and K02DA043063.The work of WenlongZhang was partially supported by a Bisgrove Scholar Award.
Publisher Copyright:
© 2017 IEEE.
PY - 2017/8/14
Y1 - 2017/8/14
N2 - As our population ages, neurological impairments and degeneration of the musculoskeletal system yield gait abnormalities, which can significantly reduce quality of life. Gait rehabilitative therapy has been widely adopted to help patients maximize community participation and living independence. To further improve the precision and efficiency of rehabilitative therapy, more objective methods need to be developed based on sensory data. In this paper, an algorithmic framework is proposed to provide classification of gait disorders caused by two common neurological diseases, stroke and Parkinson's Disease (PD), from ground contact force (GCF) data. An advanced machine learning method, multi-task feature learning (MTFL), is used to jointly train classification models of a subject's gait in three classes, post-stroke, PD and healthy gait. Gait parameters related to mobility, balance, strength and rhythm are used as features for the classification. Out of all the features used, the MTFL models capture the more important ones per disease, which will help provide better objective assessment and therapy progress tracking. To evaluate the proposed methodology we use data from a human participant study, which includes five PD patients, three post-stroke patients, and three healthy subjects. Despite the diversity of abnormalities, the evaluation shows that the proposed approach can successfully distinguish post-stroke and PD gait from healthy gait, as well as post-stroke from PD gait, with Area Under the Curve (AUC) score of at least 0.96. Moreover, the methodology helps select important gait features to better understand the key characteristics that distinguish abnormal gaits and design personalized treatment.
AB - As our population ages, neurological impairments and degeneration of the musculoskeletal system yield gait abnormalities, which can significantly reduce quality of life. Gait rehabilitative therapy has been widely adopted to help patients maximize community participation and living independence. To further improve the precision and efficiency of rehabilitative therapy, more objective methods need to be developed based on sensory data. In this paper, an algorithmic framework is proposed to provide classification of gait disorders caused by two common neurological diseases, stroke and Parkinson's Disease (PD), from ground contact force (GCF) data. An advanced machine learning method, multi-task feature learning (MTFL), is used to jointly train classification models of a subject's gait in three classes, post-stroke, PD and healthy gait. Gait parameters related to mobility, balance, strength and rhythm are used as features for the classification. Out of all the features used, the MTFL models capture the more important ones per disease, which will help provide better objective assessment and therapy progress tracking. To evaluate the proposed methodology we use data from a human participant study, which includes five PD patients, three post-stroke patients, and three healthy subjects. Despite the diversity of abnormalities, the evaluation shows that the proposed approach can successfully distinguish post-stroke and PD gait from healthy gait, as well as post-stroke from PD gait, with Area Under the Curve (AUC) score of at least 0.96. Moreover, the methodology helps select important gait features to better understand the key characteristics that distinguish abnormal gaits and design personalized treatment.
KW - gait analysis
KW - gait disorder diagnosis
KW - gait pattern recognition
KW - multi-task learning
UR - http://www.scopus.com/inward/record.url?scp=85029359133&partnerID=8YFLogxK
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U2 - 10.1109/CHASE.2017.78
DO - 10.1109/CHASE.2017.78
M3 - Conference contribution
AN - SCOPUS:85029359133
T3 - Proceedings - 2017 IEEE 2nd International Conference on Connected Health: Applications, Systems and Engineering Technologies, CHASE 2017
SP - 195
EP - 204
BT - Proceedings - 2017 IEEE 2nd International Conference on Connected Health
PB - Institute of Electrical and Electronics Engineers Inc.
T2 - 2nd IEEE International Conference on Connected Health: Applications, Systems and Engineering Technologies, CHASE 2017
Y2 - 17 July 2017 through 19 July 2017
ER -