TY - JOUR
T1 - Child- and family-focused cognitive-behavioral therapy for pediatric bipolar disorder
T2 - A randomized clinical trial
AU - West, Amy E.
AU - Weinstein, Sally M.
AU - Peters, Amy T.
AU - Katz, Andrea C.
AU - Henry, David B.
AU - Cruz, Rick A.
AU - Pavuluri, Mani N.
N1 - Funding Information:
The authors thank Patrick Tolan, PhD, of the University of Virginia, and David Miklowitz, PhD, of the University of California at Los Angeles, for mentorship and consultation; Christine Celio, PhD, and Jackie Doxie, MA, of the University of Illinois at Chicago, for serving as study coordinators. The authors thank all of the psychology, psychiatry, and social work trainees and staff at the University of Illinois at Chicago that served as study therapists and/or supervisors. The authors also thank all of the undergraduate and graduate psychology trainees from the University of Illinois at Chicago who served as study raters and research assistants. Finally, the authors thank the University of Illinois Center for Clinical and Translational Science (CCTS) for resources to support this study. The CCTS is supported by the National Center for Advancing Translational Sciences, National Institutes of Health (NIH), through grant UL1TR000050. The work of the Center is solely the responsibility of the authors and does not necessarily represent the official views of NIH.
Publisher Copyright:
© 2014 American Academy of Child and Adolescent Psychiatry.
PY - 2014
Y1 - 2014
N2 - Objective: Previous studies have found that family-based psychosocial treatments are effective adjuncts to pharmacotherapy among adults and adolescents with bipolar disorder (BD). The objective of this study was to compare the efficacy of adjunctive child- and family-focused cognitive-behavioral therapy (CFF-CBT) to psychotherapy as usual (control) for mood symptom severity and global functioning in children with BD. Method: Sixty-nine youth, aged 7 to 13 years (mean = 9.19, SD = 1.61) with DSM-IV-TR bipolar I, II, or not otherwise specified (NOS) disorder were randomly assigned to CFF-CBT or control groups. Both treatments consisted of 12 weekly sessions followed by 6 monthly booster sessions delivered over a total of 9 months. Independent evaluators assessed participants at baseline, week 4, week 8, week 12 (posttreatment), and week 39 (6-month follow-up). Results: Participants in CFF-CBT attended more sessions, were less likely to drop out, and reported greater satisfaction with treatment than controls. CFF-CBT demonstrated efficacy compared to the control treatment in reducing parent-reported mania at posttreatment and depression symptoms at posttreatment and follow-up. Global functioning did not differ at posttreatment but was higher among CFF-CBT participants at follow-up. Conclusion: CFF-CBT may be efficacious in reducing acute mood symptoms and improving long-term psychosocial functioning among children with BD.
AB - Objective: Previous studies have found that family-based psychosocial treatments are effective adjuncts to pharmacotherapy among adults and adolescents with bipolar disorder (BD). The objective of this study was to compare the efficacy of adjunctive child- and family-focused cognitive-behavioral therapy (CFF-CBT) to psychotherapy as usual (control) for mood symptom severity and global functioning in children with BD. Method: Sixty-nine youth, aged 7 to 13 years (mean = 9.19, SD = 1.61) with DSM-IV-TR bipolar I, II, or not otherwise specified (NOS) disorder were randomly assigned to CFF-CBT or control groups. Both treatments consisted of 12 weekly sessions followed by 6 monthly booster sessions delivered over a total of 9 months. Independent evaluators assessed participants at baseline, week 4, week 8, week 12 (posttreatment), and week 39 (6-month follow-up). Results: Participants in CFF-CBT attended more sessions, were less likely to drop out, and reported greater satisfaction with treatment than controls. CFF-CBT demonstrated efficacy compared to the control treatment in reducing parent-reported mania at posttreatment and depression symptoms at posttreatment and follow-up. Global functioning did not differ at posttreatment but was higher among CFF-CBT participants at follow-up. Conclusion: CFF-CBT may be efficacious in reducing acute mood symptoms and improving long-term psychosocial functioning among children with BD.
KW - Cognitive-behavioral therapy
KW - Family-focused intervention
KW - Pediatric bipolar disorder
KW - Randomized clinical trial
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U2 - 10.1016/j.jaac.2014.08.013
DO - 10.1016/j.jaac.2014.08.013
M3 - Article
C2 - 25440307
AN - SCOPUS:84911386907
SN - 0890-8567
VL - 53
SP - 1168-1178.e1
JO - Journal of the American Academy of Child and Adolescent Psychiatry
JF - Journal of the American Academy of Child and Adolescent Psychiatry
IS - 11
ER -