Catalysis by the RNA subunit of RNase P - a minireview

S. Altman, M. F. Baer, M. Bartkiewicz, H. Gold, C. Guerrier-Takada, L. A. Kirsebom, N. Lumelsky, K. Peck

Research output: Contribution to journalArticlepeer-review

34 Scopus citations


RNase P, an enzyme that contains both RNA and protein components, cleaves tRNA precursors to generate mature 5′ termini. The catalytic activity of RNase P resides in the RNA component, with the protein cofactor affecting the rate of the cleavage reaction. The reaction is also influenced by the nature of the tRNA substrate.

Original languageEnglish (US)
Pages (from-to)63-64
Number of pages2
Issue number1
StatePublished - Oct 15 1989
Externally publishedYes


  • Catalytic RNA
  • M1 RNA structure and function
  • model substrates
  • nucleotide sequences
  • protein cofactor

ASJC Scopus subject areas

  • Genetics


Dive into the research topics of 'Catalysis by the RNA subunit of RNase P - a minireview'. Together they form a unique fingerprint.

Cite this