Biomarker-predicted sugars intake compared with self-reported measures in US Hispanics/Latinos: Results from the HCHS/SOL SOLNAS study

JM Beasley, M. Jung, Natasha Tasevska, WW Wong, AM Siega-Riz, D. Sotres-Alvarez, MD Gellman, JR Kizer, PA Shaw, J. Stamler, M. Stoutenberg, L. Van Horn, AA Franke, J. Wylie-Rosett, Y. Mossavar-Rahmani

    Research output: Contribution to journalArticlepeer-review

    10 Scopus citations


    Objective Measurement error in self-reported total sugars intake may obscure associations between sugars consumption and health outcomes, and the sum of 24 h urinary sucrose and fructose may serve as a predictive biomarker of total sugars intake. Design The Study of Latinos: Nutrition & Physical Activity Assessment Study (SOLNAS) was an ancillary study to the Hispanic Community Health Study/Study of Latinos (HCHS/SOL) cohort. Doubly labelled water and 24 h urinary sucrose and fructose were used as biomarkers of energy and sugars intake, respectively. Participants' diets were assessed by up to three 24 h recalls (88 % had two or more recalls). Procedures were repeated approximately 6 months after the initial visit among a subset of ninety-six participants. Setting Four centres (Bronx, NY; Chicago, IL; Miami, FL; San Diego, CA) across the USA. Subjects Men and women (n 477) aged 18-74 years. Results The geometric mean of total sugars was 167·5 (95 % CI 154·4, 181·7) g/d for the biomarker-predicted and 90·6 (95 % CI 87·6, 93·6) g/d for the self-reported total sugars intake. Self-reported total sugars intake was not correlated with biomarker-predicted sugars intake (r=-0·06, P=0·20, n 450). Among the reliability sample (n 90), the reproducibility coefficient was 0·59 for biomarker-predicted and 0·20 for self-reported total sugars intake. Conclusions Possible explanations for the lack of association between biomarker-predicted and self-reported sugars intake include measurement error in self-reported diet, high intra-individual variability in sugars intake, and/or urinary sucrose and fructose may not be a suitable proxy for total sugars intake in this study population.

    Original languageEnglish (US)
    Pages (from-to)3256-3264
    Number of pages9
    JournalPublic Health Nutrition
    Issue number18
    StatePublished - Dec 1 2016


    • Doubly labelled water
    • Hispanics/Latinos
    • Keywords Sugars
    • Self-report
    • Urinary sucrose and fructose biomarkers

    ASJC Scopus subject areas

    • Medicine (miscellaneous)
    • Nutrition and Dietetics
    • Public Health, Environmental and Occupational Health


    Dive into the research topics of 'Biomarker-predicted sugars intake compared with self-reported measures in US Hispanics/Latinos: Results from the HCHS/SOL SOLNAS study'. Together they form a unique fingerprint.

    Cite this