Bacterial safety of a closed-administration system for enteral nutrition solution

L. A. Vaughan, M. Manore, D. H. Winston

    Research output: Contribution to journalArticlepeer-review

    14 Scopus citations


    The purpose of this study was to investigate the bacterial integrity of a newly designed closed-administration system for enteral formula delivery. Three clinical simulations, designated Phases I, II, and III, were tested: dispersal of (I) 3 L formula over a 24-hour period, (II) 2 L formula over a 24-hour period, period, and (III) 2 L formula over a 48-hour period. Within each 24- or 48-hour simulation phase, a single administration set was used. Samples were withdrawn for bacterial analysis at 4- or 8-hour intervals. Simulations and samplings were completed under controlled, but not aseptic, conditions. Results indicated that bacterial growth was significant across all three simulation phases. Re-utilization of the administration set did not introduce bacterial contamination into subsequent liters of formula. Alcohol cleansing of the administration set was not found to be necessary for maintenance of bacterial closed integrity. Even when administered over a 24- or 48-hour period, the formula dispersed through this closed system did not develop any significant degree of bacterial growth. Results of this study suggest that this newly designed system for the administration of enteral formula significantly minimizes the risk of bacterial contamination.

    Original languageEnglish (US)
    Pages (from-to)35-37
    Number of pages3
    JournalJournal of the American Dietetic Association
    Issue number1
    StatePublished - Jan 1 1988

    ASJC Scopus subject areas

    • Food Science
    • Nutrition and Dietetics


    Dive into the research topics of 'Bacterial safety of a closed-administration system for enteral nutrition solution'. Together they form a unique fingerprint.

    Cite this