Assessing the effect of natural selection in malaria parasites

Ananias A. Escalante, Omar E. Cornejo, Ascanio Rojas, Venkatachalam Udhayakumar, Altaf A. Lal

Research output: Contribution to journalReview articlepeer-review

97 Scopus citations


There are few concepts that have been used across disciplines; one of them is natural selection. The impact that this process has on parasite genetic diversity is reviewed here by discussing examples on drug resistance and vaccine antigens. Emphasis is made on how mechanisms need to be addressed rather than associations, and how such investigations were out of reach of biomedical researchers only a decade ago.

Original languageEnglish (US)
Pages (from-to)388-395
Number of pages8
JournalTrends in Parasitology
Issue number8
StatePublished - Aug 1 2004
Externally publishedYes

ASJC Scopus subject areas

  • Parasitology
  • Infectious Diseases


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