Abstract
Both Baileya multiradiata Harv. and Gray (Compositae) and Baileya pleniradiata Harv. and Gray have been shown to produce the cytotoxic and antineoplastic pseudoguaianolide radiatin (1). The crystal and molecular structure has been determined from single-crystal x-ray intensity data. The structure was solved by direct methods and refined by full-matrix least squares to a residual of 0.081 for 1589 independent observed reflections. The compound crystallizes in the monoclinic space group P21 Z = 2, with lattice parameters a = 6.614 (3), b = 9.185 (4), c = 15.567 (5) Å, and β = 102.03 (1)°. A most probable absolute stereochemical assignment was made by comparison with known and very similar natural products.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 3544-3548 |
| Number of pages | 5 |
| Journal | Journal of the American Chemical Society |
| Volume | 100 |
| Issue number | 11 |
| DOIs | |
| State | Published - 1978 |
ASJC Scopus subject areas
- Catalysis
- Chemistry(all)
- Biochemistry
- Colloid and Surface Chemistry