Antineoplastic agents, 162.1 zephyranthes candida

George Pettit, Gordon M. Cragg, Sheo Bux Singh, James A. Duke, Dennis L. Doubek

Research output: Contribution to journalArticlepeer-review

85 Scopus citations


The Chinese medicinal plant Zephyranthes candida was found to contain a cytostatic constituent. Separation of a n-BuOH extract directed by results of a bioassay employing the P-388 lymphocytic leukemia led to trans-dihydronarciclasine [2] as the principal cytostatic agent with ED50 3.2 X 10-3 μ-g/ml.

Original languageEnglish (US)
Pages (from-to)176-178
Number of pages3
JournalJournal of Natural Products
Issue number1
StatePublished - 1990

ASJC Scopus subject areas

  • Analytical Chemistry
  • Molecular Medicine
  • Pharmacology
  • Pharmaceutical Science
  • Drug Discovery
  • Complementary and alternative medicine
  • Organic Chemistry


Dive into the research topics of 'Antineoplastic agents, 162.1 zephyranthes candida'. Together they form a unique fingerprint.

Cite this