Animal Models of Parkinson's Disease: The Non-Motor and Non-Dopaminergic Features

Katherine E. Soderstrom, Shilpa Ramaswamy, C. Warren Olanow, Jeffrey H. Kordower

Research output: Chapter in Book/Report/Conference proceedingChapter

Original languageEnglish (US)
Title of host publicationParkinson's Disease
Subtitle of host publicationNon-Motor and Non-Dopaminergic Features
PublisherBlackwell Publishing Ltd
Number of pages14
ISBN (Print)9781405191852
StatePublished - Jun 27 2011
Externally publishedYes


  • Animal models of Parkinson's disease - non-motor and non-dopaminergic features
  • Animal models, assessing non-motor - and non-dopaminergic features of PD
  • Braak and colleagues's pattern of α-synuclein pathology - in aging control
  • Classic models of PD - 6-Hydroxydopamine (6-OHDA), dopamine analog via dopamine transporter
  • Neuropsychiatric dysfunction - depression, comorbidities associated with PD
  • Novel models of PD - genetic models of PD
  • Parkinson's disease (PD) - resting tremor, rigidity, bradykinesia and gait disturbance
  • PD pathology, well beyond nigrostriatal dopamine system
  • Sleep disturbance, as symptom of PD - problematic for PD patients
  • Visual hallucinations, debilitating side effects - of dopamine replacement

ASJC Scopus subject areas

  • Neuroscience(all)

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