Adjunctive and Alternative Treatment of Circadian Rhythm Sleep Disorders

C. E. Kline, S. D. Youngstedt

Research output: Chapter in Book/Report/Conference proceedingChapter


Circadian rhythm sleep disorders (CRSDs) are caused by a misalignment between the endogenous circadian timing system and the desired/required sleep-wake schedule. Treatment usually focuses on shifting the circadian system to align with the desired sleep-wake schedule or on ways to alleviate sleep impairment during sleep periods and decreased alertness during wake periods. Bright light and melatonin are the dominant therapies used in treating CRSDs. Alternative methods to shifting the circadian system involve the manipulation of the sleep-wake schedule and the use of nonphotic cues such as exercise, food timing, and arousal. However, little is known regarding the proper timing of these stimuli for shifting the circadian system, and there has been minimal investigation of their use with specific CRSDs. As a result, most specific treatment recommendations for CRSDs involve combinations of bright light, melatonin, and/or sleep-wake manipulations.

Original languageEnglish (US)
Title of host publicationEncyclopedia of Sleep
PublisherElsevier Inc.
Number of pages6
ISBN (Electronic)9780123786111
ISBN (Print)9780123786104
StatePublished - Jan 1 2013
Externally publishedYes


  • Advanced sleep phase type
  • Bright light
  • Circadian rhythm sleep disorder
  • Circadian rhythms
  • Delayed sleep phase type
  • Exercise
  • Free-running type
  • Irregular sleep-wake type
  • Jet lag type
  • Melatonin
  • Nonphotic entrainment
  • Shift-work type

ASJC Scopus subject areas

  • Medicine (miscellaneous)


Dive into the research topics of 'Adjunctive and Alternative Treatment of Circadian Rhythm Sleep Disorders'. Together they form a unique fingerprint.

Cite this