Abstract
Preventing non-adherence and treating adherence failure are important to consider in designing community-based clinical trials. The approach and methods for managing adherence are vital. This paper describes a practical and theoretically-based strategy for managing adherence in a small cancer prevention trial with subjects (n = 40) taking a non-steroidal anti- inflammatory drug, piroxicam. Average daily pill intake adherence was exceptionally high (97.4%) as measured by self-report calendar. Thus, the generalized adherence enhancement approach used in this study may have been a related factor, although statistical model-testing was not possible in this small trial. The generalized intervention took into account factors such as the potential barriers and benefits of being in the study, self-efficacy and satisfaction with the participant/staff relationship. These and other theoretical variables were incorporated into an overall adherence strategy that is discussed.
Original language | English (US) |
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Pages (from-to) | 15-23 |
Number of pages | 9 |
Journal | Patient Education and Counseling |
Volume | 28 |
Issue number | 1 |
DOIs | |
State | Published - Jun 1996 |
Keywords
- Adherence
- Cancer prevention
- Compliance
ASJC Scopus subject areas
- General Medicine