A family-based probabilistic method for capturing de novo mutations from high-throughput short-read sequencing data

Mathematics

• High Throughput 100%
• Pedigree 93%
• Probabilistic Methods 86%
• Sequencing 85%
• Mutation 71%
• Genotype 33%
• Family 33%
• Genome 31%
• Human 25%
• DNA Sequencing 22%
• Genetic Variation 22%
• Genomics 16%
• Posterior Probability 16%
• Estimate 13%
• Entire 12%
• Simulation 9%
• Framework 8%

Medicine & Life Sciences

• Pedigree 78%
• Mutation 40%
• Genotype 20%
• Technology 18%
• Nuclear Family 15%
• Mutation Rate 15%
• Human Genome 15%
• Genetic Variation 13%
• High-Throughput Nucleotide Sequencing 13%
• Genome 9%
• Population 5%