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Optimization of Methylene Blue Derivatives as Mitochondrial Therapeutic Agents for the Treatment of Freidreich's Ataxia
Khdour, Omar
(PI)
Hecht, Sidney
(CoI)
Bioenergetics, Center for (BE)
Molecular Sciences, School of (SMS)
Project
:
Research project
Overview
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Keyphrases
Ataxia
100%
Mitochondrial Therapeutics
100%
Methylene Blue
100%
Therapeutic Agents
100%
Friedreich Ataxia
85%
Frataxin
42%
Drugability
14%
Hereditary Neurodegenerative Diseases
14%
Pharmacokinetic Profile
14%
Methylene Violet
14%
Effective Therapy
14%
Model Stability
14%
Cellular Models
14%
Mitochondrial Function
14%
Oral Administration
14%
Lymphocytes
14%
Oral Bioavailability
14%
Metabolic Stability
14%
Preclinical Development
14%
Oxidative Stress
14%
Pharmacology, Toxicology and Pharmaceutical Science
Ataxia
100%
Carbene
100%
Friedreich's Ataxia
85%
Frataxin
42%
Bioavailability
14%
New Methylene Blue
14%
Degenerative Disease
14%
Pharmacokinetics
14%