Additional file 1: of The synthetic histone-binding regulator protein PcTF activates interferon genes in breast cancer cells

Figure S1. Comparisons of gene sets that are differentially or similarly expressed in BT-474, MCF7, BT-549, and MCF10A. Figure S2. Comparisons, by cell line, of expressed and silenced genes within PRC-modules. Figure S3. Jensen Shannon divergence analyses of transcription profiling data (RNA-seq) for all PcTF-treated and untreated cell samples. Figure S4. Detailed view of the transcription factor (TF) binding motif overrepresentation plot from Figure 3D. Figure S5. Expression levels of putative regulators of PUGs. Figure S6. Chromosome plot of PcTF-responsive genes that were identified in the RNA-seq experiment. Figure S7. Detailed view of MCF7 ChIP-seq signals. Table S1. The set of 45 H3K27me3-enriched, repressed (FPKM < 2) genes shared by the three cancer cell lines. Table S2. TF motif enrichment analysis results for the data shown in Fig. 3d. Table S3. Primers used to generate the RT-qPCR results shown in Fig. 6. (DOCX 3056 kb)