Vegetables, unsaturated fats, moderate alcohol intake, and mild cognitive impairment

Rosebud O. Roberts; Yonas E. Geda; James R. Cerhan; David S. Knopman; Ruth H. Cha; Teresa J.H. Christianson; V. Shane Pankratz; Robert J. Ivnik; Bradley F. Boeve; Helen M. O'Connor; Ronald C. Petersen

doi:10.1159/000305099

Vegetables, unsaturated fats, moderate alcohol intake, and mild cognitive impairment

Rosebud O. Roberts, Yonas E. Geda, James R. Cerhan, David S. Knopman, Ruth H. Cha, Teresa J.H. Christianson, V. Shane Pankratz, Robert J. Ivnik, Bradley F. Boeve, Helen M. O'Connor, Ronald C. Petersen

Research output: Contribution to journal › Article › peer-review

129 Scopus citations

Abstract

Background/Aims: To investigate associations of the Mediterranean diet (MeDi) components and the MeDi score with mild cognitive impairment (MCI). Methods: Participants (aged 70-89 years) were clinically evaluated to assess MCI and dementia, and completed a 128-item food frequency questionnaire. Results: 163 of 1,233 nondemented persons had MCI. The odds ratio of MCI was reduced for high vegetable intake [0.66 (95% CI = 0.44-0.99), p = 0.05] and for high mono- plus polyunsaturated fatty acid to saturated fatty acid ratio [0.52 (95% CI = 0.33-0.81), p = 0.007], adjusted for confounders. The risk of incident MCI or dementia was reduced in subjects with a high MeDi score [hazard ratio = 0.75 (95% CI = 0.46-1.21), p = 0.24]. Conclusion: Vegetables, unsaturated fats, and a high MeDi score may be beneficial to cognitive function.

Original language	English (US)
Pages (from-to)	413-423
Number of pages	11
Journal	Dementia and Geriatric Cognitive Disorders
Volume	29
Issue number	5
DOIs	https://doi.org/10.1159/000305099
State	Published - Jun 2010
Externally published	Yes

Keywords

Dietary intake
Incidence studies
Longitudinal
Mediterranean diet
Mild cognitive impairment
Moderate alcohol intake
Population-based
Prevalence studies
Unsaturated fatty acids

ASJC Scopus subject areas

Geriatrics and Gerontology
Cognitive Neuroscience
Psychiatry and Mental health

Access to Document

10.1159/000305099

Cite this

@article{e0972a1ec47b459d9920863d90d1ad7e,

title = "Vegetables, unsaturated fats, moderate alcohol intake, and mild cognitive impairment",

abstract = "Background/Aims: To investigate associations of the Mediterranean diet (MeDi) components and the MeDi score with mild cognitive impairment (MCI). Methods: Participants (aged 70-89 years) were clinically evaluated to assess MCI and dementia, and completed a 128-item food frequency questionnaire. Results: 163 of 1,233 nondemented persons had MCI. The odds ratio of MCI was reduced for high vegetable intake [0.66 (95% CI = 0.44-0.99), p = 0.05] and for high mono- plus polyunsaturated fatty acid to saturated fatty acid ratio [0.52 (95% CI = 0.33-0.81), p = 0.007], adjusted for confounders. The risk of incident MCI or dementia was reduced in subjects with a high MeDi score [hazard ratio = 0.75 (95% CI = 0.46-1.21), p = 0.24]. Conclusion: Vegetables, unsaturated fats, and a high MeDi score may be beneficial to cognitive function.",

keywords = "Dietary intake, Incidence studies, Longitudinal, Mediterranean diet, Mild cognitive impairment, Moderate alcohol intake, Population-based, Prevalence studies, Unsaturated fatty acids",

author = "Roberts, {Rosebud O.} and Geda, {Yonas E.} and Cerhan, {James R.} and Knopman, {David S.} and Cha, {Ruth H.} and Christianson, {Teresa J.H.} and Pankratz, {V. Shane} and Ivnik, {Robert J.} and Boeve, {Bradley F.} and O'Connor, {Helen M.} and Petersen, {Ronald C.}",

year = "2010",

month = jun,

doi = "10.1159/000305099",

language = "English (US)",

volume = "29",

pages = "413--423",

journal = "Dementia and Geriatric Cognitive Disorders",

issn = "1420-8008",

publisher = "S. Karger AG",

number = "5",

}

TY - JOUR

T1 - Vegetables, unsaturated fats, moderate alcohol intake, and mild cognitive impairment

AU - Roberts, Rosebud O.

AU - Geda, Yonas E.

AU - Cerhan, James R.

AU - Knopman, David S.

AU - Cha, Ruth H.

AU - Christianson, Teresa J.H.

AU - Pankratz, V. Shane

AU - Ivnik, Robert J.

AU - Boeve, Bradley F.

AU - O'Connor, Helen M.

AU - Petersen, Ronald C.

PY - 2010/6

Y1 - 2010/6

N2 - Background/Aims: To investigate associations of the Mediterranean diet (MeDi) components and the MeDi score with mild cognitive impairment (MCI). Methods: Participants (aged 70-89 years) were clinically evaluated to assess MCI and dementia, and completed a 128-item food frequency questionnaire. Results: 163 of 1,233 nondemented persons had MCI. The odds ratio of MCI was reduced for high vegetable intake [0.66 (95% CI = 0.44-0.99), p = 0.05] and for high mono- plus polyunsaturated fatty acid to saturated fatty acid ratio [0.52 (95% CI = 0.33-0.81), p = 0.007], adjusted for confounders. The risk of incident MCI or dementia was reduced in subjects with a high MeDi score [hazard ratio = 0.75 (95% CI = 0.46-1.21), p = 0.24]. Conclusion: Vegetables, unsaturated fats, and a high MeDi score may be beneficial to cognitive function.

AB - Background/Aims: To investigate associations of the Mediterranean diet (MeDi) components and the MeDi score with mild cognitive impairment (MCI). Methods: Participants (aged 70-89 years) were clinically evaluated to assess MCI and dementia, and completed a 128-item food frequency questionnaire. Results: 163 of 1,233 nondemented persons had MCI. The odds ratio of MCI was reduced for high vegetable intake [0.66 (95% CI = 0.44-0.99), p = 0.05] and for high mono- plus polyunsaturated fatty acid to saturated fatty acid ratio [0.52 (95% CI = 0.33-0.81), p = 0.007], adjusted for confounders. The risk of incident MCI or dementia was reduced in subjects with a high MeDi score [hazard ratio = 0.75 (95% CI = 0.46-1.21), p = 0.24]. Conclusion: Vegetables, unsaturated fats, and a high MeDi score may be beneficial to cognitive function.

KW - Dietary intake

KW - Incidence studies

KW - Longitudinal

KW - Mediterranean diet

KW - Mild cognitive impairment

KW - Moderate alcohol intake

KW - Population-based

KW - Prevalence studies

KW - Unsaturated fatty acids

UR - http://www.scopus.com/inward/record.url?scp=77952474582&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=77952474582&partnerID=8YFLogxK

U2 - 10.1159/000305099

DO - 10.1159/000305099

M3 - Article

C2 - 20502015

AN - SCOPUS:77952474582

SN - 1420-8008

VL - 29

SP - 413

EP - 423

JO - Dementia and Geriatric Cognitive Disorders

JF - Dementia and Geriatric Cognitive Disorders

IS - 5

ER -

Vegetables, unsaturated fats, moderate alcohol intake, and mild cognitive impairment

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this