Trapping a transition state in a computationally designed protein bottle

Keyphrases

• 3D Structure 33%
• Biphenyl 66%
• Biphenylalanine 66%
• Bond Rotation 33%
• Carbon-carbon Bond 33%
• Central Carbon 33%
• Chemical Reaction 33%
• Computational Design Analysis 33%
• Computational Protein Design 33%
• Computational Structural Analysis 33%
• Coplanar 33%
• Designed Proteins 100%
• Diffraction Methods 33%
• Directly Observed 33%
• Noncanonical Amino Acids 33%
• Packing Interactions 33%
• Planar Transitions 33%
• Pyrococcus Abyssi 33%
• Rosetta 33%
• Side Chain 66%
• Software Design 33%
• Synthetase 33%
• Thermophiles 33%
• Transfer RNA (tRNA) 33%
• Transition State 100%
• Transition State Conformation 33%
• Van Der Waals Interaction 33%
• X-ray Crystallography 33%

Biochemistry, Genetics and Molecular Biology

• Amino Acids 50%
• Conformation 100%
• Lifespan 50%
• Protein Design 50%
• Pyrococcus abyssi 50%
• Thermophile 50%
• Transfer RNA 50%

Chemistry

• Protein Design 25%