Three new alkaloids, convolutamines F and G, and convolutamydine E, from the Floridian marine bryozoan Amathia convoluta

Yoshiaki Kamano; Ayano Kotake; Hirofumi Hashima; Ichiro Hayakawa; Hatsue Hiraide; Hui Ping Zhang; Haruhisa Kizu; Kanki Komiyama; Masahiko Hayashi; George Pettit

doi:10.1135/cccc19991147

Three new alkaloids, convolutamines F and G, and convolutamydine E, from the Floridian marine bryozoan Amathia convoluta

Yoshiaki Kamano
, Ayano Kotake
, Hirofumi Hashima
, Ichiro Hayakawa
, Hatsue Hiraide
, Hui Ping Zhang
, Haruhisa Kizu
, Kanki Komiyama
, Masahiko Hayashi
, George Pettit

Molecular Sciences, School of (SMS)

Research output: Contribution to journal › Article › peer-review

41 Scopus citations

Abstract

Two new (2-phenylethyl)amine alkaloids, convolutamines F and G, and a dibromohydroxy-oxindole alkaloid, convolutamydine E, have been isolated from the butan-1-ol soluble material of the Floridian marine bryozoan Amathia convoluta. Their structures were elucidated on the basis of spectroscopic data. Convolutamine F exhibited activity against KB, KB/VJ-300, and U937 cells. This compound also exhibited the inhibitory effects for cell division of fertilized sea urchin eggs.

Original language	English (US)
Pages (from-to)	1147-1153
Number of pages	7
Journal	Collection of Czechoslovak Chemical Communications
Volume	64
Issue number	7
DOIs	https://doi.org/10.1135/cccc19991147
State	Published - Jan 1 1999

Keywords

(2-phenylethyl)amine alkaloids
3-hydroxyindol-2(3H)-one
Amathia convoluta
Bryozoa
Convolutamine F
Convolutamine G
Convolutamydine E
Cytostatic activity
Isolation
Marine natural products

ASJC Scopus subject areas

General Chemistry

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10.1135/cccc19991147

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@article{271333c095a848ce9bd23fec2d4c1374,

title = "Three new alkaloids, convolutamines F and G, and convolutamydine E, from the Floridian marine bryozoan Amathia convoluta",

abstract = "Two new (2-phenylethyl)amine alkaloids, convolutamines F and G, and a dibromohydroxy-oxindole alkaloid, convolutamydine E, have been isolated from the butan-1-ol soluble material of the Floridian marine bryozoan Amathia convoluta. Their structures were elucidated on the basis of spectroscopic data. Convolutamine F exhibited activity against KB, KB/VJ-300, and U937 cells. This compound also exhibited the inhibitory effects for cell division of fertilized sea urchin eggs.",

keywords = "(2-phenylethyl)amine alkaloids, 3-hydroxyindol-2(3H)-one, Amathia convoluta, Bryozoa, Convolutamine F, Convolutamine G, Convolutamydine E, Cytostatic activity, Isolation, Marine natural products",

author = "Yoshiaki Kamano and Ayano Kotake and Hirofumi Hashima and Ichiro Hayakawa and Hatsue Hiraide and Zhang, \{Hui Ping\} and Haruhisa Kizu and Kanki Komiyama and Masahiko Hayashi and George Pettit",

year = "1999",

month = jan,

day = "1",

doi = "10.1135/cccc19991147",

language = "English (US)",

volume = "64",

pages = "1147--1153",

journal = "Collection of Czechoslovak Chemical Communications",

issn = "0010-0765",

publisher = "Czech Academy of Sciences",

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}

TY - JOUR

T1 - Three new alkaloids, convolutamines F and G, and convolutamydine E, from the Floridian marine bryozoan Amathia convoluta

AU - Kamano, Yoshiaki

AU - Kotake, Ayano

AU - Hashima, Hirofumi

AU - Hayakawa, Ichiro

AU - Hiraide, Hatsue

AU - Zhang, Hui Ping

AU - Kizu, Haruhisa

AU - Komiyama, Kanki

AU - Hayashi, Masahiko

AU - Pettit, George

PY - 1999/1/1

Y1 - 1999/1/1

N2 - Two new (2-phenylethyl)amine alkaloids, convolutamines F and G, and a dibromohydroxy-oxindole alkaloid, convolutamydine E, have been isolated from the butan-1-ol soluble material of the Floridian marine bryozoan Amathia convoluta. Their structures were elucidated on the basis of spectroscopic data. Convolutamine F exhibited activity against KB, KB/VJ-300, and U937 cells. This compound also exhibited the inhibitory effects for cell division of fertilized sea urchin eggs.

AB - Two new (2-phenylethyl)amine alkaloids, convolutamines F and G, and a dibromohydroxy-oxindole alkaloid, convolutamydine E, have been isolated from the butan-1-ol soluble material of the Floridian marine bryozoan Amathia convoluta. Their structures were elucidated on the basis of spectroscopic data. Convolutamine F exhibited activity against KB, KB/VJ-300, and U937 cells. This compound also exhibited the inhibitory effects for cell division of fertilized sea urchin eggs.

KW - (2-phenylethyl)amine alkaloids

KW - 3-hydroxyindol-2(3H)-one

KW - Amathia convoluta

KW - Bryozoa

KW - Convolutamine F

KW - Convolutamine G

KW - Convolutamydine E

KW - Cytostatic activity

KW - Isolation

KW - Marine natural products

UR - https://www.scopus.com/pages/publications/0001189019

UR - https://www.scopus.com/pages/publications/0001189019#tab=citedBy

U2 - 10.1135/cccc19991147

DO - 10.1135/cccc19991147

M3 - Article

AN - SCOPUS:0001189019

SN - 0010-0765

VL - 64

SP - 1147

EP - 1153

JO - Collection of Czechoslovak Chemical Communications

JF - Collection of Czechoslovak Chemical Communications

IS - 7

ER -

Three new alkaloids, convolutamines F and G, and convolutamydine E, from the Floridian marine bryozoan Amathia convoluta

Abstract

Keywords

ASJC Scopus subject areas

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