The task dependent interaction of the deactivation regions

Ye Zhang, Shi Gang Feng, Hong Bo Feng, Feng Dong, Yi Yuan Tang

Research output: Contribution to journalArticlepeer-review


Although deactivation has been found frequently in former functional brain imaging researches, only recently has it become a focus of systematic study because of its not well understood physiological mechanism. However, most of the researches concentrated on the brain areas that would present deactivation, and, to our knowledge, the deactivation connectivity between these brain areas during the cognitive tasks has rarely been reported in literature. In this work, using the functional connectivity method WICA (within-condition interregional covariance analysis), we analyzed the deactivations in two different cognitive tasks-symbol orientation and number comparison. The results revealed deactivations in the posterior cingulate, precuneus, anterior cingulate and prefrontal cortex in both tasks. However, the interaction between the deactivated regions shows many differences. Our result further indicates that the potential implication of special deactivation connectivity may be related to the different task or attention resource. Further research is needed to clarify the exact reason.

Original languageEnglish (US)
Pages (from-to)1527-1532
Number of pages6
JournalChinese Science Bulletin
Issue number10
StatePublished - May 2008
Externally publishedYes


  • Deactivation
  • WICA
  • fMRI

ASJC Scopus subject areas

  • General


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