TY - JOUR
T1 - The structure of the stress-induced photosystem I–IsiA antenna supercomplex
AU - Toporik, Hila
AU - Li, Jin
AU - Williams, Dewight
AU - Chiu, Po Lin
AU - Mazor, Yuval
N1 - Funding Information:
We would like to thank N. Nelson and P. Fromme for critical reading of the manuscript, and O. Rog for many discussions. We would like to acknowledge the use of the Titan Krios at the Erying Materials Center at Arizona State University, and the funding of this instrument by the National Science Foundation (No. MRI 1531991). This study is funded by a startup grant from Arizona State University.
Publisher Copyright:
© 2019, The Author(s), under exclusive licence to Springer Nature America, Inc.
PY - 2019/6/1
Y1 - 2019/6/1
N2 - Photochemical conversion in oxygenic photosynthesis takes place in two large protein–pigment complexes named photosystem II and photosystem I (PSII and PSI, respectively). Photosystems associate with antennae in vivo to increase the size of photosynthetic units to hundreds or thousands of pigments. Regulation of the interactions between antennae and photosystems allows photosynthetic organisms to adapt to their environment. In low-iron environments, cyanobacteria express IsiA, a PSI antenna, critical to their survival. Here we describe the structure of the PSI–IsiA complex isolated from the mesophilic cyanobacterium Synechocystis sp. PCC 6803. This 2-MDa photosystem–antenna supercomplex structure reveals more than 700 pigments coordinated by 51 subunits, as well as the mechanisms facilitating the self-assembly and association of IsiA with multiple PSI assemblies.
AB - Photochemical conversion in oxygenic photosynthesis takes place in two large protein–pigment complexes named photosystem II and photosystem I (PSII and PSI, respectively). Photosystems associate with antennae in vivo to increase the size of photosynthetic units to hundreds or thousands of pigments. Regulation of the interactions between antennae and photosystems allows photosynthetic organisms to adapt to their environment. In low-iron environments, cyanobacteria express IsiA, a PSI antenna, critical to their survival. Here we describe the structure of the PSI–IsiA complex isolated from the mesophilic cyanobacterium Synechocystis sp. PCC 6803. This 2-MDa photosystem–antenna supercomplex structure reveals more than 700 pigments coordinated by 51 subunits, as well as the mechanisms facilitating the self-assembly and association of IsiA with multiple PSI assemblies.
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U2 - 10.1038/s41594-019-0228-8
DO - 10.1038/s41594-019-0228-8
M3 - Article
C2 - 31133699
AN - SCOPUS:85066946453
SN - 1545-9993
VL - 26
SP - 443
EP - 449
JO - Nature Structural and Molecular Biology
JF - Nature Structural and Molecular Biology
IS - 6
ER -