The natural history of primary biliary cirrhosis

Mohamad H. Imam, Keith Lindor

Research output: Contribution to journalArticlepeer-review

39 Scopus citations


Our understanding of the natural history of primary biliary cirrhosis (PBC) has been evolving especially following the introduction of ursodeoxycholic acid (UDCA). A clearer understanding of disease pathophysiology and earlier diagnosis with increased prevalence of the disease worldwide has led to increased interest and improved outcomes in patients with PBC. In this article, the authors touch briefly on features of the disease and describe the natural history of PBC prior to and after the introduction of UDCA.

Original languageEnglish (US)
Pages (from-to)329-333
Number of pages5
JournalSeminars in Liver Disease
Issue number3
StatePublished - Aug 2014


  • liver transplantation
  • primary biliary cirrhosis
  • ursodeoxycholic acid

ASJC Scopus subject areas

  • Hepatology


Dive into the research topics of 'The natural history of primary biliary cirrhosis'. Together they form a unique fingerprint.

Cite this