Abstract
Our understanding of the natural history of primary biliary cirrhosis (PBC) has been evolving especially following the introduction of ursodeoxycholic acid (UDCA). A clearer understanding of disease pathophysiology and earlier diagnosis with increased prevalence of the disease worldwide has led to increased interest and improved outcomes in patients with PBC. In this article, the authors touch briefly on features of the disease and describe the natural history of PBC prior to and after the introduction of UDCA.
Original language | English (US) |
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Pages (from-to) | 329-333 |
Number of pages | 5 |
Journal | Seminars in Liver Disease |
Volume | 34 |
Issue number | 3 |
DOIs | |
State | Published - Aug 2014 |
Keywords
- liver transplantation
- primary biliary cirrhosis
- ursodeoxycholic acid
ASJC Scopus subject areas
- Hepatology