The influence of detergents on the solubility of membrane proteins

M. A. Rosenow; C. L. Magee; Joann Williams; James Allen

doi:10.1107/S0907444902016736

The influence of detergents on the solubility of membrane proteins

M. A. Rosenow, C. L. Magee, Joann Williams, James Allen

Molecular Sciences, School of (SMS)

Research output: Contribution to journal › Article › peer-review

15 Scopus citations

Abstract

The dependence of protein solubility on ionic strength was measured for the bacterial reaction center in different detergents and amphiphiles. The detergent and amphiphile combinations that yielded the highest solubility of the protein are correlated with those that yield protein crystals.

Original language	English (US)
Pages (from-to)	2076-2081
Number of pages	6
Journal	Acta Crystallographica Section D: Biological Crystallography
Volume	58
Issue number	12
DOIs	https://doi.org/10.1107/S0907444902016736
State	Published - Dec 1 2002

ASJC Scopus subject areas

Structural Biology

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title = "The influence of detergents on the solubility of membrane proteins",

abstract = "The dependence of protein solubility on ionic strength was measured for the bacterial reaction center in different detergents and amphiphiles. The detergent and amphiphile combinations that yielded the highest solubility of the protein are correlated with those that yield protein crystals.",

author = "Rosenow, {M. A.} and Magee, {C. L.} and Joann Williams and James Allen",

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The influence of detergents on the solubility of membrane proteins

Abstract

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