Spatially addressable multiprotein nanoarrays templated by aptamer-tagged DNA nanoarchitectures

Rahul Chhabra, Jaswinder Sharma, Yonggang Ke, Yan Liu, Sherri Rinker, Stuart Lindsay, Hao Yan

Research output: Contribution to journalArticlepeer-review

247 Scopus citations


Here we generalize a highly programmable strategy to self-assemble multiprotein nanoarrays with deterministic positional addressability. These protein nanoarrays were templated by aptamer-tagged DNA nanoarchitectures. Arrays of proteins with precisely controlled positions and interprotein spacings offer great potential in proteomics, tissue engineering, and medical diagnostics.

Original languageEnglish (US)
Pages (from-to)10304-10305
Number of pages2
JournalJournal of the American Chemical Society
Issue number34
StatePublished - Aug 29 2007

ASJC Scopus subject areas

  • Catalysis
  • Chemistry(all)
  • Biochemistry
  • Colloid and Surface Chemistry


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