Capillary electrophoresis and similar techniques which use an electrified contracting-flow interface (gradient elution moving boundary electrophoresis, electrophoretic exclusion, for examples) are widely used, but the detailed flow dynamics and local electric field effects within this zone have only recently been quantitatively investigated. The motivating force behind this work is establishing particle flow based visualization tools enabling advances for arbitrary interfacial designs beyond this traditional flow/electric field interface. These tools work with pre-computed 2-dimensional fundamental interacting fields which govern particle and(or) fluid flow and can now be obtained from various computational fluid dynamics (CFD) software packages. The particle-flow visualization calculations implemented in the tool and are built upon a solid foundation in fluid dynamics. The module developed in here provides a simulated video particle observation tool which generates a fast check for legitimacy. Further, estimating the accuracy and precision of full 2-D and 3-D simulation is notoriously difficult and a centerline estimation is used to quickly and easily quantitate behaviors in support of decision points. This tool and the recent quantitative assessment of particle behavior within the interfacial area have set the stage for new designs which can emphasize advantageous behaviors not offered by the traditional configuration.

Original languageEnglish (US)
Title of host publicationProceedings of SPIE-IS and T Electronic Imaging - Visualization and Data Analysis 2014
StatePublished - 2014
Event21st annual IS and T/SPIE Conference on Visualization and Analysis, VDA 2014 - San Francisco, CA, United States
Duration: Feb 3 2014Feb 5 2014

Publication series

NameProceedings of SPIE - The International Society for Optical Engineering
ISSN (Print)0277-786X
ISSN (Electronic)1996-756X


Other21st annual IS and T/SPIE Conference on Visualization and Analysis, VDA 2014
Country/TerritoryUnited States
CitySan Francisco, CA


  • Electrophoretic capture
  • Particle Flow Visualization
  • Simulation

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Computer Science Applications
  • Applied Mathematics
  • Electrical and Electronic Engineering


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