TY - JOUR
T1 - Sex as a moderator of body composition following a randomized controlled lifestyle intervention among Latino youth with obesity
AU - Vander Wyst, Kiley B.
AU - Olson, Micah L.
AU - Keller, Colleen S.
AU - Soltero, Erica G.
AU - Williams, Allison N.
AU - Peña, Armando
AU - Ayers, Stephanie L.
AU - Jager, Justin
AU - Shaibi, Gabriel Q.
N1 - Funding Information:
Drs Shaibi, Olson, Keller, Soltero, Ayers, and Jager and Mrs Williams conceptualized and designed the study, coordinated and supervised data collection, and critically reviewed the manuscript for important intellectual content. Mr Pena critically reviewed the manuscript for important intellectual content. Drs Jager and Ayers supervised the initial analyses. Dr Vander Wyst performed the initial analyses, drafted the initial manuscript, and reviewed and revised the manuscript as needed. All authors approved the final manuscript as submitted and agree to be accountable for all aspects of the work. This research was funded by the National Institutes of Health/National Institute on Minority Health and Health Disparities (P20MD002316; U54MD002316). The content is solely the responsibility of the authors and does not necessarily represent the official views of the NIMHD or the NIH. Drs Vander Wyst, Soltero, Olson, and Shaibi were also supported by a grant from the National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Disease (R01 DK107579).
Publisher Copyright:
© 2020 World Obesity Federation
PY - 2020/6/1
Y1 - 2020/6/1
N2 - Background: Body composition differences between males and females emerge during adolescence and continue throughout adulthood; however, whether sex moderates body composition changes in adolescents with obesity after an intervention is unknown. Objective: To examine sex as a moderator of changes in adiposity following lifestyle intervention. Methods: A total of 136 Latino youth with obesity (BMI% 98.2 ± 1.3) aged 14 to 16 years old were randomized to either a 12-week lifestyle intervention (27 males/40 females) or control (35 males/34 females) group. The intervention included nutrition education (1 h/wk) and moderate-to-vigorous physical activity (3 h/wk). Anthropometric data (body mass index [BMI], BMI%, waist circumference, total body fat, and fat-free mass) were obtained pre- and post-intervention. Sex differences were examined by general linear models with significance determined at P <.05 for the F-statistic. Results: Sex did not moderate changes in BMI (F1,115 = 0.01, P =.9), BMI% (F1,115 = 0.14, P =.7), or waist circumference (F1,117 = 1.1, P =.3). Sex significantly moderated changes in body fat percent (F1,117 = 5.3, P =.02), fat mass (F1,116 = 4.5, P =.04), and fat-free mass (F1,116 = 4.3, P =.04). Intervention males compared with females had greater relative reductions in fat percent (−4.1 ± 0.8% vs −1.2 ± 0.7%, P =.02) and fat mass (−5.0 ± 1.1 kg vs −1.5 ± 0.9 kg, P =.02) and gained more fat free mass (3.6 ± 0.9 kg vs 0.5 ± 0.8 kg, P =.02) when compared with same sex controls. Conclusion: Males and females exhibited a differential response to lifestyle intervention for percent fat, fat mass, and fat-free mass indicating that sex-specific improvements in body composition favours males over females.
AB - Background: Body composition differences between males and females emerge during adolescence and continue throughout adulthood; however, whether sex moderates body composition changes in adolescents with obesity after an intervention is unknown. Objective: To examine sex as a moderator of changes in adiposity following lifestyle intervention. Methods: A total of 136 Latino youth with obesity (BMI% 98.2 ± 1.3) aged 14 to 16 years old were randomized to either a 12-week lifestyle intervention (27 males/40 females) or control (35 males/34 females) group. The intervention included nutrition education (1 h/wk) and moderate-to-vigorous physical activity (3 h/wk). Anthropometric data (body mass index [BMI], BMI%, waist circumference, total body fat, and fat-free mass) were obtained pre- and post-intervention. Sex differences were examined by general linear models with significance determined at P <.05 for the F-statistic. Results: Sex did not moderate changes in BMI (F1,115 = 0.01, P =.9), BMI% (F1,115 = 0.14, P =.7), or waist circumference (F1,117 = 1.1, P =.3). Sex significantly moderated changes in body fat percent (F1,117 = 5.3, P =.02), fat mass (F1,116 = 4.5, P =.04), and fat-free mass (F1,116 = 4.3, P =.04). Intervention males compared with females had greater relative reductions in fat percent (−4.1 ± 0.8% vs −1.2 ± 0.7%, P =.02) and fat mass (−5.0 ± 1.1 kg vs −1.5 ± 0.9 kg, P =.02) and gained more fat free mass (3.6 ± 0.9 kg vs 0.5 ± 0.8 kg, P =.02) when compared with same sex controls. Conclusion: Males and females exhibited a differential response to lifestyle intervention for percent fat, fat mass, and fat-free mass indicating that sex-specific improvements in body composition favours males over females.
KW - adolescents
KW - body fat percent
KW - fat mass
KW - lean mass
KW - sexual dimorphism
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U2 - 10.1111/ijpo.12620
DO - 10.1111/ijpo.12620
M3 - Article
C2 - 32072749
AN - SCOPUS:85079709849
SN - 2047-6302
VL - 15
JO - Pediatric Obesity
JF - Pediatric Obesity
IS - 6
M1 - e12620
ER -