Red cell superoxide dismutase is increased in iron deficiency anemia

Lennart T. Jansson; Mikko V. Perkkiö; Wayne T. Willis; Canio J. Refino; Peter R. Dallman

doi:10.1159/000206222

Red cell superoxide dismutase is increased in iron deficiency anemia

Lennart T. Jansson, Mikko V. Perkkiö, Wayne T. Willis, Canio J. Refino, Peter R. Dallman

Life Sciences, School of (SOLS)

Research output: Contribution to journal › Article › peer-review

40 Scopus citations

Abstract

Red blood cells (RBC) from iron-deficient rats were found to generate more malonyldialdehyde after in vitro incubation with H₂O₂ than RBC from control rats (p < 0.001). The iron-deficient RBC, however, had a higher content of superoxide dismutase (SOD) than control RBC (p < 0.02). This finding suggests an increased formation of SOD compensatory to an increased oxidant stress.

Original language	English (US)
Pages (from-to)	218-221
Number of pages	4
Journal	Acta Haematologica
Volume	74
Issue number	4
DOIs	https://doi.org/10.1159/000206222
State	Published - Jan 1 1985

Keywords

Anemia
Iron deficiency
Superoxide dismutase

ASJC Scopus subject areas

Hematology

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10.1159/000206222

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title = "Red cell superoxide dismutase is increased in iron deficiency anemia",

abstract = "Red blood cells (RBC) from iron-deficient rats were found to generate more malonyldialdehyde after in vitro incubation with H2O2 than RBC from control rats (p < 0.001). The iron-deficient RBC, however, had a higher content of superoxide dismutase (SOD) than control RBC (p < 0.02). This finding suggests an increased formation of SOD compensatory to an increased oxidant stress.",

keywords = "Anemia, Iron deficiency, Superoxide dismutase",

author = "Jansson, {Lennart T.} and Perkki{\"o}, {Mikko V.} and Willis, {Wayne T.} and Refino, {Canio J.} and Dallman, {Peter R.}",

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doi = "10.1159/000206222",

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T1 - Red cell superoxide dismutase is increased in iron deficiency anemia

AU - Jansson, Lennart T.

AU - Perkkiö, Mikko V.

AU - Willis, Wayne T.

AU - Refino, Canio J.

AU - Dallman, Peter R.

PY - 1985/1/1

Y1 - 1985/1/1

N2 - Red blood cells (RBC) from iron-deficient rats were found to generate more malonyldialdehyde after in vitro incubation with H2O2 than RBC from control rats (p < 0.001). The iron-deficient RBC, however, had a higher content of superoxide dismutase (SOD) than control RBC (p < 0.02). This finding suggests an increased formation of SOD compensatory to an increased oxidant stress.

AB - Red blood cells (RBC) from iron-deficient rats were found to generate more malonyldialdehyde after in vitro incubation with H2O2 than RBC from control rats (p < 0.001). The iron-deficient RBC, however, had a higher content of superoxide dismutase (SOD) than control RBC (p < 0.02). This finding suggests an increased formation of SOD compensatory to an increased oxidant stress.

KW - Anemia

KW - Iron deficiency

KW - Superoxide dismutase

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JO - Acta Haematologica

JF - Acta Haematologica

IS - 4

ER -

Red cell superoxide dismutase is increased in iron deficiency anemia

Abstract

Keywords

ASJC Scopus subject areas

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