Rare alleles, MHC and captive breeding

P. W. Hedrick, P. S. Miller

Research output: Chapter in Book/Report/Conference proceedingChapter


Used transferrin data in Przewalski's horses Equus przewalskii to evaluate a breeding program to select for rare alleles. One individual, 1060, has the transferrin allele J. The authors determine the effect on founder contribution of multiply mating 1060 to increase the number of copies of this allele. Since there are 485 individuals in the population at this time, this extra mating had little detrimental effect on the distribution of founder contributions and the number of founder equivalents. The authors then selected 65, an ancestor of 1060, which had a high likelihood of being the individual that passed on the J allele. At a time when the population had only 22 other individuals, even though the founder contributions were changed more, there was also little effect on the founder contributions and the number of founder equivalents. -from Authors

Original languageEnglish (US)
Title of host publicationConservation genetics
EditorsV. Loeschcke
Number of pages18
StatePublished - 1994

ASJC Scopus subject areas

  • General Agricultural and Biological Sciences
  • Genetics
  • Nature and Landscape Conservation
  • Genetics(clinical)


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