Question of the Ribosyl Moiety in the Promotion of Callus Growth by Exogenously Added Cytokinins

Sidney M. Hecht, Robert M. Bock, Ruth Y. Schmitz, Folke Skoog, Nelson J. Leonard, John L. Occolowitz

Research output: Contribution to journalArticlepeer-review

24 Scopus citations


We have examined the role of the 9 position and the influence of the 9-substituents on the cytokinin activity of N6-(isopent(en)yl)adenine derivatives. Five new cytokinin analogs have been employed in this study: 7-(3-methyl-2-butenylamino)pyrazolo[4,3-d]pyrimidine, 3-methyl-7-(3-methyl-2-butenylamino)pyrazolo[4,3-d]pyrimidine, 7-(3-methy 1-2- butenylamino)-3-β-D-ribofuranosylpyrazolo[4,3 - d]pyrimidine, 7-(3-methylbutylamino)pyrazolo[4,5 -d]pyrimidine, and 3-methyl-7-(3-methylbutylamino)pyrazolo[4,3-d]pyrimidine. Their activities have been compared with those of the corresponding purine derivatives. The relative biological activities in the tobacco bioassay suggested that the addition of a ribosyl moiety in the 9 position of exogenously supplied cytokinins is not a prerequisite for their promotion of cell division and growth of plant tissue.

Original languageEnglish (US)
Pages (from-to)4224-4228
Number of pages5
Issue number23
StatePublished - Nov 1 1971
Externally publishedYes

ASJC Scopus subject areas

  • Biochemistry


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