Properties of a maonovalent and divalent requiring endoribonuclease with novel specificity from calf heart

Eiko Akaboshi; Sidney Altman

doi:10.1093/nar/11.11.3687

Properties of a maonovalent and divalent requiring endoribonuclease with novel specificity from calf heart

Eiko Akaboshi
, Sidney Altman

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

A new sonovalent and divalent requiring endoribonuclease hat been identified in extracts of calf heart titans using a natural substrate nolecule. This ribonuclease creates 5- hydroxyl and 3- phosphate groups in its cleavage products. It cleaves predominantly between pyrimidine and A residues though not all such possible sites are attacked in the substrates tested.

Original language	English (US)
Pages (from-to)	3687-3702
Number of pages	16
Journal	Nucleic acids research
Volume	11
Issue number	11
DOIs	https://doi.org/10.1093/nar/11.11.3687
State	Published - Jun 11 1983
Externally published	Yes

ASJC Scopus subject areas

Genetics

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title = "Properties of a maonovalent and divalent requiring endoribonuclease with novel specificity from calf heart",

abstract = "A new sonovalent and divalent requiring endoribonuclease hat been identified in extracts of calf heart titans using a natural substrate nolecule. This ribonuclease creates 5- hydroxyl and 3- phosphate groups in its cleavage products. It cleaves predominantly between pyrimidine and A residues though not all such possible sites are attacked in the substrates tested.",

author = "Eiko Akaboshi and Sidney Altman",

note = "Funding Information: ACKNOWLEDGEMENTS We thank Dr. D. Luse for supplying materials needed to make the globin gene transcripts and our colleagues for many helpful suggestions. E.A. was supported in part by the Rudolph Anderson Fund of Tale University. S.A. is the receipient of USPHS grant GM 19422 and NSF grant PCM 79-04054.",

year = "1983",

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doi = "10.1093/nar/11.11.3687",

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T1 - Properties of a maonovalent and divalent requiring endoribonuclease with novel specificity from calf heart

AU - Akaboshi, Eiko

AU - Altman, Sidney

N1 - Funding Information: ACKNOWLEDGEMENTS We thank Dr. D. Luse for supplying materials needed to make the globin gene transcripts and our colleagues for many helpful suggestions. E.A. was supported in part by the Rudolph Anderson Fund of Tale University. S.A. is the receipient of USPHS grant GM 19422 and NSF grant PCM 79-04054.

PY - 1983/6/11

Y1 - 1983/6/11

N2 - A new sonovalent and divalent requiring endoribonuclease hat been identified in extracts of calf heart titans using a natural substrate nolecule. This ribonuclease creates 5- hydroxyl and 3- phosphate groups in its cleavage products. It cleaves predominantly between pyrimidine and A residues though not all such possible sites are attacked in the substrates tested.

AB - A new sonovalent and divalent requiring endoribonuclease hat been identified in extracts of calf heart titans using a natural substrate nolecule. This ribonuclease creates 5- hydroxyl and 3- phosphate groups in its cleavage products. It cleaves predominantly between pyrimidine and A residues though not all such possible sites are attacked in the substrates tested.

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DO - 10.1093/nar/11.11.3687

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JO - Nucleic acids research

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IS - 11

ER -

Properties of a maonovalent and divalent requiring endoribonuclease with novel specificity from calf heart

Abstract

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