Photocatalytic inactivation of Cryptosporidium parvum with TiO2 and low-pressure ultraviolet irradiation

Hodon Ryu, Daniel Gerrity, John C. Crittenden, Morteza Abbaszadegan

Research output: Contribution to journalArticlepeer-review

58 Scopus citations


This study investigated the efficacy of low-pressure ultraviolet (UV) irradiation and the synergistic effect of UV/titanium dioxide (TiO2) photocatalysis on Cryptosporidium parvum oocyst inactivation. At UV doses of 2.7, 8.0, and 40 mJ/cm2, oocyst inactivation was 1.3, 2.6, and 3.3 log10, respectively. Reactive oxygen species (ROS) generated by longwave UV radiation (>315 nm) and TiO2 achieved less than 0.28-log inactivation. However, the synergistic effect of germicidal (254 nm) UV and TiO2 resulted in 2-log and 3-log oocyst inactivation with 4.0 and 11.0 mJ/cm2, respectively. Therefore, using TiO2 in combination with UV reduced the dose requirement for 3-log inactivation by 56%. An approximate 1-log decrease in inactivation of oocysts was observed with nanopure water in comparison to buffered water, whereas changes in pH from 6 to 8 had little effect on the photocatalytic inactivation of oocysts in either matrix (P>0.1).

Original languageEnglish (US)
Pages (from-to)1523-1530
Number of pages8
JournalWater Research
Issue number6-7
StatePublished - Mar 2008


  • Cryptosporidium inactivation
  • Integrated cell culture quantitative PCR
  • UV/TiO photocatalysis

ASJC Scopus subject areas

  • Ecological Modeling
  • Water Science and Technology
  • Waste Management and Disposal
  • Pollution


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