P1 latency as a biomarker for central auditory development in children with hearing impairment

Anu Sharma, Kathryn Martin, Peter Roland, Paul Bauer, Melissa H. Sweeney, Phillip Gilley, Michael Dorman

Research output: Contribution to journalArticlepeer-review

141 Scopus citations


We used the latency of the P1 cortical auditory-evoked potential (CAEP) as a biomarker for the development of central auditory pathways in three children who received intervention through hearing aids and/or cochlear implants. Our goal was to examine the clinical feasibility of using the latency of the P1 CAEP as an objective tool to evaluate whether acoustic amplification for hearing-impaired children has provided sufficient stimulation for normal development of central auditory pathways. If clinicians have such a marker, then they can more confidently make a decision about whether to provide a child with a cochlear implant following an appropriate hearing-aid trial. Using the same marker, clinicians will also be able to monitor the maturation of central auditory pathways once electrical stimulation is initiated.

Original languageEnglish (US)
Pages (from-to)564-573
Number of pages10
JournalJournal of the American Academy of Audiology
Issue number8
StatePublished - 2005


  • Amplification
  • Biomarker
  • Cochlear implant
  • Cortical auditory evoked potential
  • Hearing aid
  • Hearing impairment
  • Objective measure
  • P1
  • Plasticity

ASJC Scopus subject areas

  • Speech and Hearing


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