@article{8abcff2b97544fb29611edcfaca59b81,
title = "Open data set of live cyanobacterial cells imaged using an X-ray laser",
abstract = "Structural studies on living cells by conventional methods are limited to low resolution because radiation damage kills cells long before the necessary dose for high resolution can be delivered. X-ray free-electron lasers circumvent this problem by outrunning key damage processes with an ultra-short and extremely bright coherent X-ray pulse. Diffraction-before-destruction experiments provide high-resolution data from cells that are alive when the femtosecond X-ray pulse traverses the sample. This paper presents two data sets from micron-sized cyanobacteria obtained at the Linac Coherent Light Source, containing a total of 199,000 diffraction patterns. Utilizing this type of diffraction data will require the development of new analysis methods and algorithms for studying structure and structural variability in large populations of cells and to create abstract models. Such studies will allow us to understand living cells and populations of cells in new ways. New X-ray lasers, like the European XFEL, will produce billions of pulses per day, and could open new areas in structural sciences.",
author = "{Van Der Schot}, Gijs and Martin Svenda and Maia, {Filipe R N C} and Hantke, {Max F.} and DePonte, {Daniel P.} and Seibert, {M. Marvin} and Andrew Aquila and Joachim Schulz and Richard Kirian and Mengning Liang and Francesco Stellato and Sadia Bari and Bianca Iwan and Jakob Andreasson and Nicusor Timneanu and Johan Bielecki and Daniel Westphal and {Nunes De Almeida}, Francisca and Dusko Odic and Dirk Hasse and Carlsson, {Gunilla H.} and Larsson, {Daniel S D} and Anton Barty and Martin, {Andrew V.} and Sebastian Schorb and Christoph Bostedt and Bozek, {John D.} and Sebastian Carron and Ken Ferguson and Daniel Rolles and Artem Rudenko and Epp, {Sascha W.} and Lutz Foucar and Benedikt Rudek and Benjamin Erk and Robert Hartmann and Nils Kimmel and Peter Holl and Lars Englert and Loh, {N. Duane} and Chapman, {Henry N.} and Inger Andersson and Janos Hajdu and Tomas Ekeberg",
note = "Funding Information: This work was supported by the Swedish Research Council (621-2011-5710, 2015-05007, 628-2008-1109, 828-2012-108, 822-2012-5260, 822-2010-6157, 621-2012-3404, ICA 12-0064, 621-2012-3570), the Knut and Alice Wallenberg Foundation (KAW-2011.081), the European Research Council (ERC-291602), the R{\"o}ntgen-{\AA}ngstr{\"o}m Cluster (349-2011-6488, 2015-06107, 349-2011-6497, 349-2013-574, 05K12CH1), Stiftelsen Olle Engkvist Byggm{\"a}stare, ELI-Extreme Light Infrastructure-phase 2 (CZ.02.1.01/0.0/0.0-/15-008/0000162) from European Regional Development Fund, 'The Hamburg Center for Ultrafast Imaging' of the Deutsche Forschungsgemeinschaft (CUI, DFG-EXC1074), and the Helmholtz Association through program funds to DESY. Publisher Copyright: {\textcopyright} The Author(s) 2016.",
year = "2016",
month = aug,
day = "1",
doi = "10.1038/sdata.2016.58",
language = "English (US)",
volume = "3",
journal = "Scientific Data",
issn = "2052-4463",
publisher = "Nature Publishing Group",
}