Nanostructured oxygen sensor - using micelles to incorporate a hydrophobic platinum porphyrin

Fengyu Su, Ruhaniyah Alam, Qian Mei, Yanqing Tian, Cody Youngbull, Roger H. Johnson, Deirdre Meldrum

Research output: Contribution to journalArticlepeer-review

44 Scopus citations


Hydrophobic platinum(II)-5,10,15,20-tetrakis-(2,3,4,5,6-pentafluorophenyl)-porphyrin (PtTFPP) was physically incorporated into micelles formed from poly(ε-caprolactone)-block-poly(ethylene glycol) to enable the application of PtTFPP in aqueous solution. Micelles were characterized using dynamic light scattering (DLS) and atomic force microscopy (AFM) to show an average diameter of about 140 nm. PtTFPP showed higher quantum efficiency in micellar solution than in tetrahydrofuran (THF) and dichloromethane (CH 2Cl 2). PtTFPP in micelles also exhibited higher photostability than that of PtTFPP suspended in water. PtTFPP in micelles exhibited good oxygen sensitivity and response time. This study provided an efficient approach to enable the application of hydrophobic oxygen sensors in a biological environment.

Original languageEnglish (US)
Article numbere33390
JournalPloS one
Issue number3
StatePublished - Mar 22 2012

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Agricultural and Biological Sciences(all)
  • General


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