@inproceedings{b978e1436509481f94c3ba7e365e33d3,
title = "Microscopic linear liquid streams in vacuum: Injection of solvated biological samples into X-ray free electron lasers",
abstract = "Microscopic linear liquid free-streams offer a means of gently delivering biological samples into a probe beam in vacuum while maintaining the sample species in a fully solvated state. By employing gas dynamic forces to form the microscopic liquid stream (as opposed to a conventional solid-walled convergent nozzle), liquid free-streams down to 300 nm diameter have been generated. Such {"}Gas Dynamic Virtual Nozzles{"} (GDVN) are ideally suited to injecting complex biological species into an X-ray Free Electron Laser (XFEL) to determine the structure of the biological species via Serial Femtosecond Crystallography (SFX). GDVN injector technology developed for this purpose is described.",
keywords = "Biological Structure Determination, Gas-Dynamic Virtual Nozzle, Nanocrystallography, Rayleigh Droplet Streams, Rayleigh-Plateau Instability, Serial Femtosecond Crystallography, X-ray Free Electron Laser",
author = "Doak, {R. B.} and Deponte, {D. P.} and G. Nelson and F. Camacho-Alanis and Alexandra Ros and John Spence and Uwe Weierstall",
year = "2012",
doi = "10.1063/1.4769693",
language = "English (US)",
isbn = "9780735411159",
series = "AIP Conference Proceedings",
number = "1",
pages = "1314--1323",
booktitle = "28th International Symposium on Rarefied Gas Dynamics 2012",
edition = "1",
note = "28th International Symposium on Rarefied Gas Dynamics 2012, RGD 2012 ; Conference date: 09-07-2012 Through 13-07-2012",
}