Meta-analysis for psychiatric research using free software R

Ding Geng Chen

doi:10.11919/j.issn.1002-0829.215063

Meta-analysis for psychiatric research using free software R

Ding Geng Chen

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

Summary: This paper provides a brief overview of meta-analysis (MA) with emphasis on classical fixedeffects and random-effects MA models. It illustrates the application of MA models with the open-source software R using publicly available data from five studies on lamotrigine to treat bipolar depression and finds that meta-analysis identifies a statistically significant advantage of lamotrigine over placebo that was not evident in the individual studies.

Original language	English (US)
Pages (from-to)	195-199
Number of pages	5
Journal	Shanghai Archives of Psychiatry
Volume	27
Issue number	3
DOIs	https://doi.org/10.11919/j.issn.1002-0829.215063
State	Published - Jun 1 2015
Externally published	Yes

Keywords

Bipolar disorder
Fixed-effects model
Lamotrigine
Meta-analysis
Random-effects model

ASJC Scopus subject areas

Neurology
Psychiatry and Mental health

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10.11919/j.issn.1002-0829.215063

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AB - Summary: This paper provides a brief overview of meta-analysis (MA) with emphasis on classical fixedeffects and random-effects MA models. It illustrates the application of MA models with the open-source software R using publicly available data from five studies on lamotrigine to treat bipolar depression and finds that meta-analysis identifies a statistically significant advantage of lamotrigine over placebo that was not evident in the individual studies.

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KW - Meta-analysis

KW - Random-effects model

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Meta-analysis for psychiatric research using free software R

Abstract

Keywords

ASJC Scopus subject areas

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