Mechanisms of bacterial pathogenicity

J. W. Wilson, M. J. Schurr, C. L. LeBlanc, R. Ramamurthy, K. L. Buchanan, Cheryl A. Nickerson

Research output: Contribution to journalReview articlepeer-review

191 Scopus citations


Pathogenic bacteria utilise a number of mechanisms to cause disease in human hosts. Bacterial pathogens express a wide range of molecules that bind host cell targets to facilitate a variety of different host responses. The molecular strategies used by bacteria to interact with the host can be unique to specific pathogens or conserved across several different species. A key to fighting bacterial disease is the identification and characterisation of all these different strategies. The availability of complete genome sequences for several bacterial pathogens coupled with bioinformatics will lead to significant advances toward this goal.

Original languageEnglish (US)
Pages (from-to)216-224
Number of pages9
JournalPostgraduate Medical Journal
Issue number918
StatePublished - 2002
Externally publishedYes

ASJC Scopus subject areas

  • Medicine(all)


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