Mechanism of the Base-Induced Decomposition of iV-Nitroso-iV-methylurea

Sidney M. Hecht, John W. Kozarich

Research output: Contribution to journalArticlepeer-review

38 Scopus citations


The mechanism corresponding to the base-induced decomposition of N-nitroso-N-methylurea is discussed. Evidence is presented for the decomposition which is consistent with initial abstraction of a urea proton, but not with a mechanism involving initial nucleophilic addition to the nitroso or carbonyl groups.

Original languageEnglish (US)
Pages (from-to)1821-1824
Number of pages4
JournalJournal of Organic Chemistry
Issue number10
StatePublished - May 1 1973
Externally publishedYes

ASJC Scopus subject areas

  • Organic Chemistry


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