Mass spectrometric immunoassay revisited

Randall W. Nelson; Chad Borges

doi:10.1007/s13361-011-0094-z

Mass spectrometric immunoassay revisited

Randall W. Nelson, Chad Borges

Research output: Contribution to journal › Article › peer-review

34 Scopus citations

Abstract

The progressive understanding and improvement of matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOFMS), realized over the years through the considerable efforts of Dr. Marvin Vestal, have made possible numerous comparable efforts involving its application in the biological sciences. Here we revisit the concepts behind one such analytical approach, Mass Spectrometric Immunoassay, which is designed to selectively detect and quantify proteins present in biological milieu.

Original language	English (US)
Pages (from-to)	960-968
Number of pages	9
Journal	Journal of the American Society for Mass Spectrometry
Volume	22
Issue number	6
DOIs	https://doi.org/10.1007/s13361-011-0094-z
State	Published - Jun 2011

Keywords

Affinity capture
Clinical and Diagnostic Mass Spectrometry
MALDI-TOF
Marvin Vestal
Protein Quantification

ASJC Scopus subject areas

Structural Biology
Spectroscopy

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10.1007/s13361-011-0094-z

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KW - Protein Quantification

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Mass spectrometric immunoassay revisited

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

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