Marine animal and terrestrial plant anticancer constituentsa

George Pettit

Research output: Contribution to journalArticlepeer-review

90 Scopus citations


Substantial advances in improving human cancer treatment continue to require discovery and development of new and curative anticancer drugs. Our recent (1989–93) progress in discovery and development of new anticancer drugs derived from marine animal and terrestrial plant biosynthetic products has been reviewed. Special emphasis was placed upon the bryostatin (1,2), dolastatin (4–6), halichondrin (15), halistatin (16,17), spongistatin (18–20), cephalostatin (7–14) and pancratistatin (34) series of potentially useful anticancer drugs.

Original languageEnglish (US)
Pages (from-to)2271-2281
Number of pages11
JournalPure and Applied Chemistry
Issue number10-11
StatePublished - Jan 1 1994

ASJC Scopus subject areas

  • General Chemistry
  • General Chemical Engineering


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