@inproceedings{5cdce7c6df624fdfba8b43f18b4a8fdd,
title = "Live single cell rotation using hydrodynamic microvortex flow and optical trapping",
abstract = "We present a method to stably rotate cells about a rotation axis perpendicular to the imaging axis, using a combination of hydrodynamic microvortex flow and optical trapping on a microfluidic chip. We present theoretical simulations, fabrication, system setup, rotation imaging, and data analysis. A tilted backside exposure technique was used to fabricate trapezoidal features which form the site for microvortical flow. Optical trapping was used to hold the cell in this flow, thereby stabilizing cell rotation. The integrated setup can be utilized for 3D single cell imaging with sub-micron isotropic spatial resolution.",
keywords = "Fluorescence imaging, Microvortex, Optical tweezers, Single cell rotation",
author = "Shetty, \{R. M.\} and Myers, \{J. R.\} and Teller, \{W. L.\} and A. Shabilla and D. Smith and J. Houkal and J. Vela and Shih-Hui Chao and Johnson, \{R. H.\} and L. Kelbauskas and H. Wang and Deirdre Meldrum",
note = "Publisher Copyright: {\textcopyright} 14CBMS.; 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014 ; Conference date: 26-10-2014 Through 30-10-2014",
year = "2014",
language = "English (US)",
series = "18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014",
publisher = "Chemical and Biological Microsystems Society",
pages = "1545--1547",
booktitle = "18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014",
}