Isolation and structure of phakellistatin 2 from the eastern indian ocean marine sponge phakellia carteri

  • George Pettit
  • , Rui Tan
  • , Michael D. Williams
  • , Larry Tackett
  • , Jean M. Schmidt
  • , Ronald L. Cerny
  • , John N A Hooper

Research output: Contribution to journalArticlepeer-review

49 Scopus citations

Abstract

The marine sponge Phakellia carteri indigenous to the Republic of the Comoros was found to contain a new cell growth inhibitory (P388 cell line ED50 0.34 μg/ml) cyclo-heptapeptide named phakellistatin 2.

Original languageEnglish (US)
Pages (from-to)2869-2874
Number of pages6
JournalBioorganic and Medicinal Chemistry Letters
Volume3
Issue number12
DOIs
StatePublished - Dec 1993

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Medicine
  • Molecular Biology
  • Pharmaceutical Science
  • Drug Discovery
  • Clinical Biochemistry
  • Organic Chemistry

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