Innate and Adaptive Immunity: The Immune Response to Foreign Materials

Benjamin George Keselowsky, Abhinav Acharya, Jamal S. Lewis

Research output: Chapter in Book/Report/Conference proceedingChapter

10 Scopus citations


The immune system is the defense mechanism of the body that is responsible for protecting against damaging foreign pathogens, maintaining components of self and permitting benign commensal microbes. Primary components and functions of innate and adaptive immunity and how the immune system recognizes and eliminates or reacts to foreign bodies at an introductory level are presented in this chapter. Components of the immune system which differentiate between “self” and “non-self” along with mechanisms for elimination of the recognized threat are described. With these basic immunology concepts in mind, the biomaterials scientist can be better prepared to anticipate issues which arise at the biomaterials–tissue interface. Finally, areas of particular interest to biomaterials and biomaterials-centric applications are described.

Original languageEnglish (US)
Title of host publicationBiomaterials Science
Subtitle of host publicationAn Introduction to Materials in Medicine
Number of pages29
ISBN (Electronic)9780128161371
ISBN (Print)9780128161388
StatePublished - Jan 1 2020


  • Adaptive immunity
  • Immune system
  • Immunology
  • Innate immunity
  • Leukocyte
  • Lymphocyte

ASJC Scopus subject areas

  • General Medicine
  • General Biochemistry, Genetics and Molecular Biology


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